Exercise Pill: Gain without Pain!?

Exercise Pill: Gain without Pain!?

This video was inspired by a recent article one of my clients showed me titled, “The Exercise Pill: The search for a drug to replace workouts” from the Nov 6, 2017 edition of the New Yorker. I read the article and found it very intriguing but also very confirming with a lot of my own research and application of this evidence. I’ve known about PPAR’s and Irisin for years, and here comes an article talking about these same fat-burning substances. Well, in this video I summarize the key points of the article along with providing my own evidence of how we can achieve improved health and leanness through a plant-based diet (doesn’t need to be vegan) and effective exercise (HIIT and/or low-moderate intensity interval training).

References:

1) PPARδ: a dagger in the heart of the metabolic syndrome-

2) Roles of peroxisome proliferator-activated receptor delta (PPARdelta) in the control of fatty acid catabolism. A new target for the treatment of metabolic syndrome-

3) PPARδ Promotes Running Endurance by Preserving Glucose-

4) Exercise Mimetics: Running Without a Road Map-

5) Exercise in a Pill: The Latest on Exercise-Mimetics-

6) Re-examination of the contribution of substrates to energy expenditure during high-intensity intermittent exercise in endurance athletes-

7) Fat metabolism during high-intensity exercise in endurance-trained and untrained men-

8) Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients-

9) Mitochondrial gene expression in elite cyclists: effects of high-intensity interval exercise-

10) Dietary fiber prevents obesity-related liver lipotoxicity by modulating sterol-regulatory element binding protein pathway in C57BL/6J mice fed a high-fat/cholesterol diet-

11) Irisin: A renaissance in metabolism?- t